Endocrine Abstracts

Introduction: Adrenal insufficiency (AI) is a potential life-threatening emergency with patients presenting with hypovolaemic shock. Although glucocorticoid-induced AI is well known, there are only a few reports of other drug-induced aetiologies.Case Report: A 50-year-old HIV-positive Caucasian female on ritonavir, darunavir, abacavir and lamivudine presented generally unwell with dizziness on standing, fatigue and weakness. Two days prior to admission, ...

Background: Hypercalcaemia is defined as an elevated serum calcium level above 2.6 mmol/l and occurs in 1 in 1000 of the population. It commonly results from primary hyperparathyroidism (PHP) which is usually treated with parathyroidectomy. A less common cause of hypercalcaemia is familial hypocalciuric hypercalcaemia (FHH) which is caused by mutations inactivating the calcium-sensing receptor; however FHH is relatively benign and requires no treatment. It is clearly important...